2021 Mercedes-Benz GLS vs 2022 Honda Odyssey

The “S” in the 2021 Mercedes-Benz GLS name is meant to connect the SUV to the S-Class flagship sedan. In this sense, the GLS is the S-Class of SUVs, and it delivers on that positioning. The 2021 GLS-Class has three rows of spacious seating, and puts comfort above all else. The GLS can hold groceries, weekend bags, antique desks purchased from a roadside consignment shop—all things that would require a lot of negotiating in the S-Class sedan.

The GLS is one member of a growing fraternity of full-size, three-row, luxury SUVs. Their ranks include the Cadillac Escalade, Lincoln Navigator, Infiniti QX80, and the more recent BMW X7. The GLS sets itself apart with a higher standard of luxury, and impressive performance… if you’re willing to shell out the cash.

If you are a minivan aficionado like we are, then you know that the 2022 Honda Odyssey is the most enjoyable one to drive. It has that light, effortless, responsive driving character that Honda bakes into every one of its cars, trucks, SUVs, and minivans. But you also know that the Odyssey’s rivals are successfully outflanking it in terms of stylish design, all-weather capability, electrified efficiency, infotainment technology, and outright luxury.

In response to these new threats, Honda makes no changes to the 2022 Odyssey. Good thing its “original recipe” approach remains pretty tasty.