Driver side window rolls down by itself and right rear passenger door won't unlock

Steph...look, no offense, but check your Owner's Manual to help rule this potential solution. Take a peek at the child safety locks inside the rear doors. If they are on...you can't open doors from inside handles. Make sure they are off, they can interfere.

As far as the window rolling down by itself, which is what pressing the button down can do, you may have a short. The power window switch can be exposed to moisture, which could degrade the wire or switch. You decide how important it is to replace the power window and/or locks module. Also, check the dome light option switches on the headliner to make sure it is in the right position (Off-Door-On) for your needs or stuck in between.