2012 F F150 power window issue

It sounds like your problem is regular as clockwork which would possibly eliminate a defective switch, frayed or broken wire. In newer vehicles power is supplied through either a general electrical module (GEM) or a body control module (BCM). These could be easily checked by a technician with a live data recorder plugged into the dash. As a preliminary check, you can check for voltage and ground at the master control on the drivers door using a multi meter. You can also check for proper operation of the switch with the same meter.

Thanks! I'll have my mechanic take a look.